{"id":1110,"date":"2017-09-21T17:04:31","date_gmt":"2017-09-21T17:04:31","guid":{"rendered":"http:\/\/www3.uah.es\/dianas\/journal\/?p=1110"},"modified":"2026-08-31T23:29:51","modified_gmt":"2026-08-31T21:29:51","slug":"dianas-6-2","status":"publish","type":"post","link":"https:\/\/dianas.web.uah.es\/journal\/dianas-6-2\/","title":{"rendered":"Dianas 6(2)"},"content":{"rendered":"\n<style type='text\/css'>\n.featured-image {display:none;}\n.post-thumbnail {display:none;}\n\n.adj_issue_cover_thumbnail {\n\tborder: none;\n\tmax-width: 100%;\n\theight: auto;\n\tdisplay: block;\n\tbackground: #ccc;\n\ttransition: transform .2s ease-in-out;\n}\n\n@media screen and (min-width: 20em) {\n\t.adj_issue_cover_thumbnail {\n\t\twidth: 50%;\n\t}\n}\n@media screen and (min-width: 40em) {\n\t.adj_issue_cover_thumbnail {\n\t\twidth: 25%;\n\t}\n}\n<\/style>\n<h5>dianas Vol. 6 | No. 2 | Septiembre 2017<\/h5>\n<!-- h5>article+article+dianas vol 6 num 2<\/h5 -->\n<img decoding=\"async\" class=\"adj_issue_cover_thumbnail\" src=\"https:\/\/dianas.web.uah.es\/journal\/wp-content\/uploads\/2017\/09\/dianas_6_2_septiembre_2017.jpg\" alt=\"Dianas 6(2)\">\n<!-- was content --><br \/>\nMonogr\u00e1fico<\/p>\n<p><b>XI M\u00e1ster en Dianas Terap\u00e9uticas en Se\u00f1alizaci\u00f3n Celular, Investigaci\u00f3n y Desarrollo &#8211; 2016-2017<\/b><\/p>\n<p>Editores: M. J. Carmena y A. Domingo<\/p>\n<p>El presente n\u00famero incluye art\u00edculos correspondientes a Proyectos Fin de M\u00e1ster seleccionados entre los presentados y defendidos al finalizar la XI edici\u00f3n del M\u00e1ster en Dianas Terap\u00e9uticas en Se\u00f1alizaci\u00f3n Celular, Investigaci\u00f3n y Desarrollo, en el curso 2016-2017.<\/p>\n<p><h1>Tabla de contenidos<\/h1>\t\n<!-- h1>Tabla de contenidos<\/h1 -->\n\t\n<div class=\"ad_journal_issue_toc\">   \n\t<div class=\"ad_journal_issue_toc_wrap\">\n\t\t<!-- articles: -->\n<div class='ad_journal_issue_toc_article' \n\tid='dianas-2017-6-2-e20170902-marina-arroyo-etal-rasgrp1-promueve-la-activacion-de-la-via-pdk-1aktmtor-independientemente-de-su-actividad' \n\tonclick=\"document.location.href='https:\/\/dianas.web.uah.es\/journal\/dianas-2017-6-2-e20170902-marina-arroyo-etal-rasgrp1-promueve-la-activacion-de-la-via-pdk-1aktmtor-independientemente-de-su-actividad\/'\" \n\tonmouseover=\"this.className='ad_journal_issue_toc_article_hover'\" \n\tonmouseout=\"this.className='ad_journal_issue_toc_article'\" \n>\n\t\t  <div class='ad_journal_issue_toc_article_title' >RasGRP1 promueve la activaci\u00f3n de la v\u00eda PDK-1\/AKT\/mTOR independientemente de su actividad.<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_authors' >Marta Marina Arroyo, Javier Arranz-Nicol\u00e1s, Raquel Arcos, Antonia \u00c1vila-Flores, Isabel M\u00e9rida<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_where' ><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2017-6-2-e20170902-marina-arroyo-etal-rasgrp1-promueve-la-activacion-de-la-via-pdk-1aktmtor-independientemente-de-su-actividad\/'>dianas. 2017 Sep; 6(2):e20170902.<\/a><\/div>\n\t\t  <!-- div class='ad_journal_issue_toc_article_authors' ><a href='dianas_2017_6_2_e20170902_marina-arroyo_etal.pdf' target='_blank'>pdf<\/a><\/div -->\n\t\t  <!-- div class='ad_journal_issue_toc_article_content' ><\/div -->\n<\/div><div class='ad_journal_issue_toc_article' \n\tid='dianas-2017-6-2-e20170903-lopez-gutierrez-etal-introduccion-del-sistema-crisprcas9-en-leishmania-infantum' \n\tonclick=\"document.location.href='https:\/\/dianas.web.uah.es\/journal\/dianas-2017-6-2-e20170903-lopez-gutierrez-etal-introduccion-del-sistema-crisprcas9-en-leishmania-infantum\/'\" \n\tonmouseover=\"this.className='ad_journal_issue_toc_article_hover'\" \n\tonmouseout=\"this.className='ad_journal_issue_toc_article'\" \n>\n\t\t  <div class='ad_journal_issue_toc_article_title' >Introducci\u00f3n del sistema CRISPR\/Cas9 en <i>Leishmania infantum<\/i><\/div>\n\t\t  <div class='ad_journal_issue_toc_article_authors' >Celia L\u00f3pez Guti\u00e9rrez, Juan Carlos Garc\u00eda Soriano, H\u00e9ctor Elessar de Lucio Ortega, Antonio Jim\u00e9nez Ru\u00edz<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_where' ><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2017-6-2-e20170903-lopez-gutierrez-etal-introduccion-del-sistema-crisprcas9-en-leishmania-infantum\/'>dianas. 2017 Sep; 6(2):e20170903.<\/a><\/div>\n\t\t  <!-- div class='ad_journal_issue_toc_article_authors' ><a href='dianas_2017_6_2_e20170903_lopez-gutierrez_etal.pdf' target='_blank'>pdf<\/a><\/div -->\n\t\t  <!-- div class='ad_journal_issue_toc_article_content' ><\/div -->\n<\/div><div class='ad_journal_issue_toc_article' \n\tid='dianas-2017-6-2-e20170904-hernandez-lopez-etal-aplicacion-de-la-tecnica-de-hibridacion-genomica-comparada-en-el-diagnostico-y-seguimiento-de-los-pacientes-con-melanoma' \n\tonclick=\"document.location.href='https:\/\/dianas.web.uah.es\/journal\/dianas-2017-6-2-e20170904-hernandez-lopez-etal-aplicacion-de-la-tecnica-de-hibridacion-genomica-comparada-en-el-diagnostico-y-seguimiento-de-los-pacientes-con-melanoma\/'\" \n\tonmouseover=\"this.className='ad_journal_issue_toc_article_hover'\" \n\tonmouseout=\"this.className='ad_journal_issue_toc_article'\" \n>\n\t\t  <div class='ad_journal_issue_toc_article_title' >Aplicaci\u00f3n de la t\u00e9cnica de Hibridaci\u00f3n Gen\u00f3mica Comparada en el diagn\u00f3stico y seguimiento de los pacientes con melanoma.<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_authors' >Patricia Hern\u00e1ndez L\u00f3pez, Jos\u00e9 Luis Rodr\u00edguez Peralto, Yolanda Ruano Dom\u00ednguez<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_where' ><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2017-6-2-e20170904-hernandez-lopez-etal-aplicacion-de-la-tecnica-de-hibridacion-genomica-comparada-en-el-diagnostico-y-seguimiento-de-los-pacientes-con-melanoma\/'>dianas. 2017 Sep; 6(2):e20170904.<\/a><\/div>\n\t\t  <!-- div class='ad_journal_issue_toc_article_authors' ><a href='dianas_2017_6_2_e20170904_hernandez-lopez_etal.pdf' target='_blank'>pdf<\/a><\/div -->\n\t\t  <!-- div class='ad_journal_issue_toc_article_content' ><\/div -->\n<\/div><div class='ad_journal_issue_toc_article' \n\tid='dianas-2017-6-2-e20170905-davila-martinez-etal-estudio-de-la-senescencia-linfocitaria-t-en-pacientes-con-lesion-de-medula-espinal-cronica' \n\tonclick=\"document.location.href='https:\/\/dianas.web.uah.es\/journal\/dianas-2017-6-2-e20170905-davila-martinez-etal-estudio-de-la-senescencia-linfocitaria-t-en-pacientes-con-lesion-de-medula-espinal-cronica\/'\" \n\tonmouseover=\"this.className='ad_journal_issue_toc_article_hover'\" \n\tonmouseout=\"this.className='ad_journal_issue_toc_article'\" \n>\n\t\t  <div class='ad_journal_issue_toc_article_title' >Estudio de la senescencia linfocitaria T en pacientes con lesi\u00f3n de m\u00e9dula espinal cr\u00f3nica.<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_authors' >Sergio D\u00e1vila Mart\u00ednez, Sergio Haro Gir\u00f3n, Andrea L\u00f3pez Su\u00e1rez, Raquel Oliva Mart\u00edn, David D\u00edaz Mart\u00edn<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_where' ><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2017-6-2-e20170905-davila-martinez-etal-estudio-de-la-senescencia-linfocitaria-t-en-pacientes-con-lesion-de-medula-espinal-cronica\/'>dianas. 2017 Sep; 6(2):e20170905.<\/a><\/div>\n\t\t  <!-- div class='ad_journal_issue_toc_article_authors' ><a href='dianas_2017_6_2_e20170905_davila-martinez_etal.pdf' target='_blank'>pdf<\/a><\/div -->\n\t\t  <!-- div class='ad_journal_issue_toc_article_content' ><\/div -->\n<\/div><div class='ad_journal_issue_toc_article' \n\tid='dianas-2017-6-2-e20170906-benitez-fernandez-etal-modulacion-de-la-patologia-de-tdp-43-por-inhibidores-selectivos-de-ttbk1' \n\tonclick=\"document.location.href='https:\/\/dianas.web.uah.es\/journal\/dianas-2017-6-2-e20170906-benitez-fernandez-etal-modulacion-de-la-patologia-de-tdp-43-por-inhibidores-selectivos-de-ttbk1\/'\" \n\tonmouseover=\"this.className='ad_journal_issue_toc_article_hover'\" \n\tonmouseout=\"this.className='ad_journal_issue_toc_article'\" \n>\n\t\t  <div class='ad_journal_issue_toc_article_title' >Modulaci\u00f3n de la patolog\u00eda de TDP-43 por inhibidores selectivos de TTBK1.<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_authors' >Roc\u00edo Ben\u00edtez Fern\u00e1ndez, Loreto Mart\u00ednez Gonz\u00e1lez, Vanesa Nozal Garc\u00eda, \u00c1ngeles Mart\u00edn-Requero, Ana Mart\u00ednez Gil<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_where' ><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2017-6-2-e20170906-benitez-fernandez-etal-modulacion-de-la-patologia-de-tdp-43-por-inhibidores-selectivos-de-ttbk1\/'>dianas. 2017 Sep; 6(2):e20170906.<\/a><\/div>\n\t\t  <!-- div class='ad_journal_issue_toc_article_authors' ><a href='dianas_2017_6_2_e20170906_benitez-fernandez_etal.pdf' target='_blank'>pdf<\/a><\/div -->\n\t\t  <!-- div class='ad_journal_issue_toc_article_content' ><\/div -->\n<\/div><div class='ad_journal_issue_toc_article' \n\tid='dianas-2017-6-2-e20170907-benitez-fernandez-etal-busqueda-de-farmacos-multidiana-en-el-tratamiento-del-alzheimer-proyecto-teorico' \n\tonclick=\"document.location.href='https:\/\/dianas.web.uah.es\/journal\/dianas-2017-6-2-e20170907-benitez-fernandez-etal-busqueda-de-farmacos-multidiana-en-el-tratamiento-del-alzheimer-proyecto-teorico\/'\" \n\tonmouseover=\"this.className='ad_journal_issue_toc_article_hover'\" \n\tonmouseout=\"this.className='ad_journal_issue_toc_article'\" \n>\n\t\t  <div class='ad_journal_issue_toc_article_title' >B\u00fasqueda de f\u00e1rmacos multidiana en el tratamiento del Alzheimer (proyecto te\u00f3rico).<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_authors' >Roc\u00edo Ben\u00edtez Fern\u00e1ndez, Alberto Langtry Y\u00e1\u00f1ez, Celia L\u00f3pez Guti\u00e9rrez, Bel\u00e9n Ortiz del Castillo, Altea Soto Neira<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_where' ><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2017-6-2-e20170907-benitez-fernandez-etal-busqueda-de-farmacos-multidiana-en-el-tratamiento-del-alzheimer-proyecto-teorico\/'>dianas. 2017 Sep; 6(2):e20170907.<\/a><\/div>\n\t\t  <!-- div class='ad_journal_issue_toc_article_authors' ><a href='dianas_2017_6_2_e20170907_benitez-fernandez_etal.pdf' target='_blank'>pdf<\/a><\/div -->\n\t\t  <!-- div class='ad_journal_issue_toc_article_content' ><\/div -->\n<\/div>\n\t<\/div><!-- \/.ad_journal_issue_toc_wrap -->\n<\/div><!-- \/ad_.journal_issue_toc -->\t\n\t\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":5641,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[43,4,2],"tags":[],"class_list":["post-1110","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dianas-vol-6-num-2","category-issue","category-vols-1-9"],"_links":{"self":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts\/1110","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/comments?post=1110"}],"version-history":[{"count":1,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts\/1110\/revisions"}],"predecessor-version":[{"id":5642,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts\/1110\/revisions\/5642"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/media\/5641"}],"wp:attachment":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/media?parent=1110"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/categories?post=1110"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/tags?post=1110"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}