{"id":214,"date":"2013-09-11T01:00:41","date_gmt":"2013-09-10T23:00:41","guid":{"rendered":"http:\/\/www3.uah.es\/dianas\/journal\/?p=214"},"modified":"2026-08-31T23:25:06","modified_gmt":"2026-08-31T21:25:06","slug":"dianas-2-2","status":"publish","type":"post","link":"https:\/\/dianas.web.uah.es\/journal\/dianas-2-2\/","title":{"rendered":"Dianas 2(2)"},"content":{"rendered":"\n<style type='text\/css'>\n.featured-image {display:none;}\n.post-thumbnail {display:none;}\n\n.adj_issue_cover_thumbnail {\n\tborder: none;\n\tmax-width: 100%;\n\theight: auto;\n\tdisplay: block;\n\tbackground: #ccc;\n\ttransition: transform .2s ease-in-out;\n}\n\n@media screen and (min-width: 20em) {\n\t.adj_issue_cover_thumbnail {\n\t\twidth: 50%;\n\t}\n}\n@media screen and (min-width: 40em) {\n\t.adj_issue_cover_thumbnail {\n\t\twidth: 25%;\n\t}\n}\n<\/style>\n<h5>dianas Vol. 2 | No. 2 | Septiembre 2013<\/h5>\n<!-- h5>article+article+dianas vol 2 num 2<\/h5 -->\n<img decoding=\"async\" class=\"adj_issue_cover_thumbnail\" src=\"https:\/\/dianas.web.uah.es\/journal\/wp-content\/uploads\/2013\/09\/dianas_2_2_septiembre_2013.jpg\" alt=\"Dianas 2(2)\">\n<!-- was content --><br \/>\nMonogr\u00e1fico<\/p>\n<p><b>VII M\u00e1ster en Dianas Terap\u00e9uticas en Se\u00f1alizaci\u00f3n Celular, Investigaci\u00f3n y Desarrollo &#8211; 2012-2013<\/b><\/p>\n<p>Editores: M. J. Carmena y A. Domingo<\/p>\n<p>El presente n\u00famero incluye art\u00edculos correspondientes a Proyectos Fin de M\u00e1ster seleccionados entre los presentados y defendidos al finalizar la s\u00e9ptima edici\u00f3n del M\u00e1ster en Dianas Terap\u00e9uticas en Se\u00f1alizaci\u00f3n Celular, Investigaci\u00f3n y Desarrollo, en el curso 2012-2013.<br \/>\n<h1>Tabla de contenidos<\/h1>\t\n<!-- h1>Tabla de contenidos<\/h1 -->\n\t\n<div class=\"ad_journal_issue_toc\">   \n\t<div class=\"ad_journal_issue_toc_wrap\">\n\t\t<!-- articles: -->\n<div class='ad_journal_issue_toc_article' \n\tid='dianas-2013-2-2-e20130901-bousono-rubio-obtencion-de-farmacos-antitumorales-a-partir-de-organismos-de-origen-marino-jaspamida-un-peptido-procedente-de-la-esponja-jaspis-sp' \n\tonclick=\"document.location.href='https:\/\/dianas.web.uah.es\/journal\/dianas-2013-2-2-e20130901-bousono-rubio-obtencion-de-farmacos-antitumorales-a-partir-de-organismos-de-origen-marino-jaspamida-un-peptido-procedente-de-la-esponja-jaspis-sp\/'\" \n\tonmouseover=\"this.className='ad_journal_issue_toc_article_hover'\" \n\tonmouseout=\"this.className='ad_journal_issue_toc_article'\" \n>\n\t\t  <div class='ad_journal_issue_toc_article_title' >Obtenci\u00f3n de f\u00e1rmacos antitumorales a partir de organismos de origen marino: Jaspamida, un p\u00e9ptido procedente de la esponja <i>Jaspis<\/i> sp.<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_authors' >Virginia Bouso\u00f1o Rubio<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_where' ><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2013-2-2-e20130901-bousono-rubio-obtencion-de-farmacos-antitumorales-a-partir-de-organismos-de-origen-marino-jaspamida-un-peptido-procedente-de-la-esponja-jaspis-sp\/'>Dianas. 2013 Sep; 2(2):e20130901.<\/a><\/div>\n\t\t  <!-- div class='ad_journal_issue_toc_article_authors' ><a href='dianas_2013_2_2_e20130901_bousono-rubio.pdf' target='_blank'>pdf<\/a><\/div -->\n\t\t  <!-- div class='ad_journal_issue_toc_article_content' ><\/div -->\n<\/div><div class='ad_journal_issue_toc_article' \n\tid='dianas-2013-2-2-e20130902-del-monte-monge-etal-regulacion-de-la-expresion-de-lamina-ac-en-la-celula-t-y-su-papel-en-la-diferenciacion-de-cd4-naive-a-celula-efectora' \n\tonclick=\"document.location.href='https:\/\/dianas.web.uah.es\/journal\/dianas-2013-2-2-e20130902-del-monte-monge-etal-regulacion-de-la-expresion-de-lamina-ac-en-la-celula-t-y-su-papel-en-la-diferenciacion-de-cd4-naive-a-celula-efectora\/'\" \n\tonmouseover=\"this.className='ad_journal_issue_toc_article_hover'\" \n\tonmouseout=\"this.className='ad_journal_issue_toc_article'\" \n>\n\t\t  <div class='ad_journal_issue_toc_article_title' >Regulaci\u00f3n de la expresi\u00f3n de lamina A\/C en la c\u00e9lula T y su papel en la diferenciaci\u00f3n de CD4  na\u00efve a c\u00e9lula efectora.<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_authors' >Alberto Del Monte Monge, Marta Blanco Berrocal, Jos\u00e9 Mar\u00eda Gonz\u00e1lez Granado, Vicente Andr\u00e9s<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_where' ><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2013-2-2-e20130902-del-monte-monge-etal-regulacion-de-la-expresion-de-lamina-ac-en-la-celula-t-y-su-papel-en-la-diferenciacion-de-cd4-naive-a-celula-efectora\/'>Dianas. 2013 Sep; 2(2):e20130902.<\/a><\/div>\n\t\t  <!-- div class='ad_journal_issue_toc_article_authors' ><a href='dianas_2013_2_2_e20130902_del-monte-monge_etal.pdf' target='_blank'>pdf<\/a><\/div -->\n\t\t  <!-- div class='ad_journal_issue_toc_article_content' ><\/div -->\n<\/div><div class='ad_journal_issue_toc_article' \n\tid='dianas-2013-2-2-e20130903-garcia-centeno-y-coello-molinero-aislamiento-purificacion-y-elucidacion-de-productos-naturales-con-actividad-antitumoral-a-partir-de-organismos-marinos-axinyssmide-a-y-axin' \n\tonclick=\"document.location.href='https:\/\/dianas.web.uah.es\/journal\/dianas-2013-2-2-e20130903-garcia-centeno-y-coello-molinero-aislamiento-purificacion-y-elucidacion-de-productos-naturales-con-actividad-antitumoral-a-partir-de-organismos-marinos-axinyssmide-a-y-axin\/'\" \n\tonmouseover=\"this.className='ad_journal_issue_toc_article_hover'\" \n\tonmouseout=\"this.className='ad_journal_issue_toc_article'\" \n>\n\t\t  <div class='ad_journal_issue_toc_article_title' >Aislamiento, purificaci\u00f3n y elucidaci\u00f3n de productos naturales con actividad antitumoral a partir de organismos marinos. Axinyssmide A y Axinyssmide C.<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_authors' >Antonio Garc\u00eda Centeno, Laura Coello Molinero<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_where' ><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2013-2-2-e20130903-garcia-centeno-y-coello-molinero-aislamiento-purificacion-y-elucidacion-de-productos-naturales-con-actividad-antitumoral-a-partir-de-organismos-marinos-axinyssmide-a-y-axin\/'>Dianas. 2013 Sep; 2(2):e20130903.<\/a><\/div>\n\t\t  <!-- div class='ad_journal_issue_toc_article_authors' ><a href='dianas_2013_2_2_e20130903_garcia-centeno_y_coello-molinero.pdf' target='_blank'>pdf<\/a><\/div -->\n\t\t  <!-- div class='ad_journal_issue_toc_article_content' ><\/div -->\n<\/div><div class='ad_journal_issue_toc_article' \n\tid='dianas-2013-2-2-e20130904-lopez-garcia-etal-evaluacion-de-la-seguridad-y-expediente-de-informacion-del-producto-cosmetico' \n\tonclick=\"document.location.href='https:\/\/dianas.web.uah.es\/journal\/dianas-2013-2-2-e20130904-lopez-garcia-etal-evaluacion-de-la-seguridad-y-expediente-de-informacion-del-producto-cosmetico\/'\" \n\tonmouseover=\"this.className='ad_journal_issue_toc_article_hover'\" \n\tonmouseout=\"this.className='ad_journal_issue_toc_article'\" \n>\n\t\t  <div class='ad_journal_issue_toc_article_title' >Evaluaci\u00f3n de la seguridad y expediente de informaci\u00f3n del producto cosm\u00e9tico.<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_authors' >Alicia L\u00f3pez Garc\u00eda, Tamara Mar\u00eda Louz\u00e1n Pardo, Sonia Gonz\u00e1lez Cesisergue<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_where' ><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2013-2-2-e20130904-lopez-garcia-etal-evaluacion-de-la-seguridad-y-expediente-de-informacion-del-producto-cosmetico\/'>Dianas. 2013 Sep; 2(2):e20130904.<\/a><\/div>\n\t\t  <!-- div class='ad_journal_issue_toc_article_authors' ><a href='dianas_2013_2_2_e20130904_lopez-garcia_etal.pdf' target='_blank'>pdf<\/a><\/div -->\n\t\t  <!-- div class='ad_journal_issue_toc_article_content' ><\/div -->\n<\/div><div class='ad_journal_issue_toc_article' \n\tid='dianas-2013-2-2-e20130905-romera-etal-bases-moleculares-de-la-selectividad-de-ligandos-por-receptores-de-melatonina' \n\tonclick=\"document.location.href='https:\/\/dianas.web.uah.es\/journal\/dianas-2013-2-2-e20130905-romera-etal-bases-moleculares-de-la-selectividad-de-ligandos-por-receptores-de-melatonina\/'\" \n\tonmouseover=\"this.className='ad_journal_issue_toc_article_hover'\" \n\tonmouseout=\"this.className='ad_journal_issue_toc_article'\" \n>\n\t\t  <div class='ad_journal_issue_toc_article_title' >Bases moleculares de la selectividad de ligandos por receptores de melatonina.<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_authors' >Julia A. Romera, \u00c1lvaro Cort\u00e9s-Cabrera, Pedro A. S\u00e1nchez-Murcia, Julio \u00c1lvarez-Builla, Federico Gago<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_where' ><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2013-2-2-e20130905-romera-etal-bases-moleculares-de-la-selectividad-de-ligandos-por-receptores-de-melatonina\/'>Dianas. 2013 Sep; 2(2):e20130905.<\/a><\/div>\n\t\t  <!-- div class='ad_journal_issue_toc_article_authors' ><a href='dianas_2013_2_2_e20130905_romera_etal.pdf' target='_blank'>pdf<\/a><\/div -->\n\t\t  <!-- div class='ad_journal_issue_toc_article_content' ><\/div -->\n<\/div><div class='ad_journal_issue_toc_article' \n\tid='dianas-2013-2-2-e20130906-sobrino-etal-efecto-de-la-queleritrina-y-de-la-ciclosporina-sobre-la-peroxidacion-lipidica-y-receptores-de-somatostatina-en-hipocampo-de-rata-con-encefalomielitis-autoinmune' \n\tonclick=\"document.location.href='https:\/\/dianas.web.uah.es\/journal\/dianas-2013-2-2-e20130906-sobrino-etal-efecto-de-la-queleritrina-y-de-la-ciclosporina-sobre-la-peroxidacion-lipidica-y-receptores-de-somatostatina-en-hipocampo-de-rata-con-encefalomielitis-autoinmune\/'\" \n\tonmouseover=\"this.className='ad_journal_issue_toc_article_hover'\" \n\tonmouseout=\"this.className='ad_journal_issue_toc_article'\" \n>\n\t\t  <div class='ad_journal_issue_toc_article_title' >Efecto de la queleritrina y de la ciclosporina sobre la peroxidaci\u00f3n lip\u00eddica y receptores de somatostatina en hipocampo de rata con encefalomielitis autoinmune experimental.<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_authors' >Carmen Sobrino, Aranzazu Peinares, Lilian Puebla Jim\u00e9nez, Eduardo Arilla Ferreiro<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_where' ><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2013-2-2-e20130906-sobrino-etal-efecto-de-la-queleritrina-y-de-la-ciclosporina-sobre-la-peroxidacion-lipidica-y-receptores-de-somatostatina-en-hipocampo-de-rata-con-encefalomielitis-autoinmune\/'>Dianas. 2013 Sep; 2(2):e20130906.<\/a><\/div>\n\t\t  <!-- div class='ad_journal_issue_toc_article_authors' ><a href='dianas_2013_2_2_e20130906_sobrino_etal.pdf' target='_blank'>pdf<\/a><\/div -->\n\t\t  <!-- div class='ad_journal_issue_toc_article_content' ><\/div -->\n<\/div><div class='ad_journal_issue_toc_article' \n\tid='dianas-2013-2-2-e20130907-vallejo-diaz-y-carrera-generacion-de-vectores-para-la-identificacion-de-interacciones-diferenciales-de-las-isoformas-de-p85' \n\tonclick=\"document.location.href='https:\/\/dianas.web.uah.es\/journal\/dianas-2013-2-2-e20130907-vallejo-diaz-y-carrera-generacion-de-vectores-para-la-identificacion-de-interacciones-diferenciales-de-las-isoformas-de-p85\/'\" \n\tonmouseover=\"this.className='ad_journal_issue_toc_article_hover'\" \n\tonmouseout=\"this.className='ad_journal_issue_toc_article'\" \n>\n\t\t  <div class='ad_journal_issue_toc_article_title' >Generaci\u00f3n de vectores para la identificaci\u00f3n de interacciones diferenciales de las isoformas de p85.<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_authors' >Jes\u00fas Vallejo D\u00edaz, Ana C. Carrera<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_where' ><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2013-2-2-e20130907-vallejo-diaz-y-carrera-generacion-de-vectores-para-la-identificacion-de-interacciones-diferenciales-de-las-isoformas-de-p85\/'>Dianas. 2013 Sep; 2(2):e20130907.<\/a><\/div>\n\t\t  <!-- div class='ad_journal_issue_toc_article_authors' ><a href='dianas_2013_2_2_e20130907_vallejo-diaz_y_carrera.pdf' target='_blank'>pdf<\/a><\/div -->\n\t\t  <!-- div class='ad_journal_issue_toc_article_content' ><\/div -->\n<\/div><div class='ad_journal_issue_toc_article' \n\tid='dianas-2013-2-2-e20130908-gonzalez-gonzalez-y-sanz-parametros-estadisticos-que-respaldan-la-calidad-de-un-ensayo-hts-a-lo-largo-de-sus-etapas-gpcr-orexigenico-como-diana' \n\tonclick=\"document.location.href='https:\/\/dianas.web.uah.es\/journal\/dianas-2013-2-2-e20130908-gonzalez-gonzalez-y-sanz-parametros-estadisticos-que-respaldan-la-calidad-de-un-ensayo-hts-a-lo-largo-de-sus-etapas-gpcr-orexigenico-como-diana\/'\" \n\tonmouseover=\"this.className='ad_journal_issue_toc_article_hover'\" \n\tonmouseout=\"this.className='ad_journal_issue_toc_article'\" \n>\n\t\t  <div class='ad_journal_issue_toc_article_title' >Par\u00e1metros estad\u00edsticos que respaldan la calidad de un ensayo HTS a lo largo de sus etapas: GPCR orexig\u00e9nico como diana.<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_authors' >Irene Gonz\u00e1lez Gonz\u00e1lez, Ana Isabel Sanz<\/div>\n\t\t  <div class='ad_journal_issue_toc_article_where' ><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2013-2-2-e20130908-gonzalez-gonzalez-y-sanz-parametros-estadisticos-que-respaldan-la-calidad-de-un-ensayo-hts-a-lo-largo-de-sus-etapas-gpcr-orexigenico-como-diana\/'>Dianas. 2013 Sep; 2(2):e20130908.<\/a><\/div>\n\t\t  <!-- div class='ad_journal_issue_toc_article_authors' ><a href='dianas_2013_2_2_e20130908_gonzalez-gonzalez_y_sanz.pdf' target='_blank'>pdf<\/a><\/div -->\n\t\t  <!-- div class='ad_journal_issue_toc_article_content' ><\/div -->\n<\/div>\n\t<\/div><!-- \/.ad_journal_issue_toc_wrap -->\n<\/div><!-- \/ad_.journal_issue_toc -->\t\n\t\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":5628,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[32,4,2],"tags":[],"class_list":["post-214","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dianas-vol-2-num-2","category-issue","category-vols-1-9"],"_links":{"self":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts\/214","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/comments?post=214"}],"version-history":[{"count":1,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts\/214\/revisions"}],"predecessor-version":[{"id":5632,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts\/214\/revisions\/5632"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/media\/5628"}],"wp:attachment":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/media?parent=214"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/categories?post=214"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/tags?post=214"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}