{"id":3954,"date":"2021-04-30T10:12:48","date_gmt":"2021-04-30T08:12:48","guid":{"rendered":"http:\/\/www3.uah.es\/secuah\/2021\/?p=700"},"modified":"2021-04-30T10:12:48","modified_gmt":"2021-04-30T08:12:48","slug":"dianas-2021-10-1-e202103a10-de-miguel-garcia-etal-estudio-del-papel-de-la-dna-polimerasa-theta-en-la-progresion-del-cancer-de-prostata-y-su-relevancia-como-diana-terapeutica","status":"publish","type":"post","link":"https:\/\/dianas.web.uah.es\/journal\/dianas-2021-10-1-e202103a10-de-miguel-garcia-etal-estudio-del-papel-de-la-dna-polimerasa-theta-en-la-progresion-del-cancer-de-prostata-y-su-relevancia-como-diana-terapeutica\/","title":{"rendered":"dianas 10 (1) de-Miguel-Garc\u00eda etal 2021 Estudio del papel de la DNA polimerasa Theta en la progresi\u00f3n del c\u00e1ncer de pr\u00f3stata y su relevancia como diana terap\u00e9utica."},"content":{"rendered":"<div class='ad_single_article'>\n<p class='ad_single_article_SO'><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-10-1\/#dianas-2021-10-1-e202103a10-de-miguel-garcia-etal-estudio-del-papel-de-la-dna-polimerasa-theta-en-la-progresion-del-cancer-de-prostata-y-su-relevancia-como-diana-terapeutica'>dianas 10(1)<br \/><\/a> &gt; <a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2021-10-1-e202103a10-de-miguel-garcia-etal-estudio-del-papel-de-la-dna-polimerasa-theta-en-la-progresion-del-cancer-de-prostata-y-su-relevancia-como-diana-terapeutica\/'>de-Miguel-Garc\u00eda etal<br \/><\/a><\/p>\n\n<p class='signature'>dianas | Vol 10 Num 1 | marzo  2021 | e202103a10<br \/><\/p>\n\n<p class='w_authors ad_single_article_authors'>Irene&nbsp;de&nbsp;Miguel&nbsp;Garc\u00eda<br&nbsp;\/>, Jos\u00e9&nbsp;M.&nbsp;Mora-Rodr\u00edguez<br&nbsp;\/>, Mar\u00eda&nbsp;Couto&nbsp;Muga<br&nbsp;\/>, Nieves&nbsp;Rodriguez&nbsp;Henche<br&nbsp;\/>, In\u00e9s&nbsp;D\u00edaz-Laviada<br&nbsp;\/>, Pedro&nbsp;A..&nbsp;Mateos-G\u00f3mez<br&nbsp;\/><\/p>\n\n<p class='w_address ad_single_article_address'>Departamento de Biolog\u00eda de Sistemas, Universidad de Alcal\u00e1. 28871, Alcal\u00e1 de Henares, Madrid, Espa\u00f1a.<br \/><\/p>\n\n<p class='w_mail ad_single_article_mail'>irenedemiguelgarcia@gmail.com<br \/><\/p>\n\n<p class='w_meeting ad_single_article_meeting'>VI Congreso de Se\u00f1alizaci\u00f3n Celular, SECUAH 2021.<br \/><br \/>\n29 de marzo a 30 de abril, 2021. Universidad de Alcal\u00e1. Alcal\u00e1 de Henares, Madrid. Espa\u00f1a.<br \/><\/p>\n\n<p class='w_abstract_caption ad_single_article_abstract_caption'>Resumen<\/p>\n<p class='w_abstract ad_single_article_abstract'>El c\u00e1ncer de pr\u00f3stata (CP) es el segundo c\u00e1ncer m\u00e1s diagnosticado y la quinta causa de muerte por c\u00e1ncer en la poblaci\u00f3n masculina. Hay pacientes que presentan enfermedad metast\u00e1sica en el momento del diagn\u00f3stico (CPm) y otros progresan hacia ese estadio durante el tratamiento. Se desconocen todos los mecanismos espec\u00edficos implicados, sin embargo, la se\u00f1alizaci\u00f3n continua del receptor de andr\u00f3genos se considera fundamental para su desarrollo, motivo por el que es la diana de los tratamientos actuales. A pesar de su eficacia, los tumores adquieren resistencia alcanzando un estado conocido como c\u00e1ncer de pr\u00f3stata resistente a la castraci\u00f3n (CPmRC), forma letal de la enfermedad.<\/p><\/p>\n\n<div class='ad_single_article_citation_box'>\n<\/div>\n\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,65,56,64],"tags":[],"class_list":["post-3954","post","type-post","status-publish","format-standard","hentry","category-article","category-dianas-vol-10-num-1","category-sesion-a","category-vols-10-19"],"_links":{"self":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts\/3954","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/comments?post=3954"}],"version-history":[{"count":0,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts\/3954\/revisions"}],"wp:attachment":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/media?parent=3954"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/categories?post=3954"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/tags?post=3954"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}