{"id":4138,"date":"2022-05-05T17:45:50","date_gmt":"2022-05-05T15:45:50","guid":{"rendered":"https:\/\/dianas.web.uah.es\/journal\/?p=4138"},"modified":"2022-05-05T17:45:50","modified_gmt":"2022-05-05T15:45:50","slug":"dianas-2022-11-1-e202203a01-lodewijk-etal-characterization-of-cd44v6-as-a-potential-target-for-newly-engineered-antibody-based-immunotherapy-for-bladder-cancer","status":"publish","type":"post","link":"https:\/\/dianas.web.uah.es\/journal\/dianas-2022-11-1-e202203a01-lodewijk-etal-characterization-of-cd44v6-as-a-potential-target-for-newly-engineered-antibody-based-immunotherapy-for-bladder-cancer\/","title":{"rendered":"dianas 11 (1) Lodewijk etal 2022 Characterization of CD44v6 as a potential target for newly engineered antibody-based immunotherapy for bladder cancer."},"content":{"rendered":"<div class='ad_single_article'>\n<p class='ad_single_article_SO'><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-11-1\/#dianas-2022-11-1-e202203a01-lodewijk-etal-characterization-of-cd44v6-as-a-potential-target-for-newly-engineered-antibody-based-immunotherapy-for-bladder-cancer'>dianas 11(1)<br \/><\/a> &gt; <a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2022-11-1-e202203a01-lodewijk-etal-characterization-of-cd44v6-as-a-potential-target-for-newly-engineered-antibody-based-immunotherapy-for-bladder-cancer\/'>Lodewijk etal<br \/><\/a><\/p>\n\n<p class='signature'>dianas | Vol 11 Num 1 | marzo  2022 | e202203a01<br \/><\/p>\n\n<p class='w_authors ad_single_article_authors'>Iris&nbsp;Lodewijk<br&nbsp;\/>, Carolina&nbsp;Rubio<br&nbsp;\/>, Omaira&nbsp;Alberquilla<br&nbsp;\/>, Rebeca&nbsp;S\u00e1nchez-Dom\u00ednguez<br&nbsp;\/>, Rosa&nbsp;Garc\u00eda-Martin<br&nbsp;\/>, Luc\u00eda&nbsp;Parrilla<br&nbsp;\/>, Luc\u00eda&nbsp;Morales<br&nbsp;\/>, Jes\u00fas&nbsp;M.&nbsp;Paramio<br&nbsp;\/>, Marta&nbsp;Due\u00f1as<br&nbsp;\/><\/p>\n\n<p class='w_address ad_single_article_address'>Fundaci\u00f3n de Investigaci\u00f3n Biom\u00e9dica Hospital 12 de Octubre \/ CIEMAT.<br \/><\/p>\n\n<p class='w_mail ad_single_article_mail'>irisadriana.lodewijk@externos.ciemat.es<br \/><\/p>\n\n<p class='w_meeting ad_single_article_meeting'>VII Congreso de Se\u00f1alizaci\u00f3n Celular, SECUAH 2022.<br \/><br \/>\n14 a 18 de marzo, 2022. Universidad de Alcal\u00e1. Alcal\u00e1 de Henares, Madrid. Espa\u00f1a.<br \/><\/p>\n\n<p class='w_abstract_caption ad_single_article_abstract_caption'>Resumen<\/p>\n<p class='w_abstract ad_single_article_abstract'>The mayor challenge of antibody efficacy as targeted cancer therapy tool consists in the selection of specific targets on tumor cells as well as the appropriated stimulatory signals to achieve correct cellular activation in the correct place at the correct time. Overexpression of CD44v6, a splice variant of CD44 glycoprotein, has been found in several tumors and has been associated with tumor progression. CD44v6 expression has also been proposed to be restricted to tumors, which emphasizes its potential as diagnostic biomarker and therapeutic target.<\/p><\/p>\n\n<div class='ad_single_article_citation_box'>\n<\/div>\n\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,6,8,94,56,64],"tags":[],"class_list":["post-4138","post","type-post","status-publish","format-standard","hentry","category-article","category-cancer","category-comunicacion-oral","category-dianas-vol-11-num-1","category-sesion-a","category-vols-10-19"],"_links":{"self":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts\/4138","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/comments?post=4138"}],"version-history":[{"count":0,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts\/4138\/revisions"}],"wp:attachment":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/media?parent=4138"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/categories?post=4138"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/tags?post=4138"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}