{"id":493,"date":"2021-04-07T09:43:23","date_gmt":"2021-04-07T07:43:23","guid":{"rendered":"http:\/\/www3.uah.es\/secuah\/2021\/?p=493"},"modified":"2021-04-07T09:43:23","modified_gmt":"2021-04-07T07:43:23","slug":"dianas-2021-10-1-e202103a04-dominguez-martin-etal-phytochemical-and-antitumoral-activity-studies-of-plectranthus-hadiensis-forssk-schweinf-ex-sprenger-aerial-parts","status":"publish","type":"post","link":"https:\/\/dianas.web.uah.es\/journal\/dianas-2021-10-1-e202103a04-dominguez-martin-etal-phytochemical-and-antitumoral-activity-studies-of-plectranthus-hadiensis-forssk-schweinf-ex-sprenger-aerial-parts\/","title":{"rendered":"dianas 10 (1) Dom\u00ednguez-Mart\u00edn etal 2021 Phytochemical and antitumoral activity studies of Plectranthus hadiensis (Forssk.) Schweinf. ex Sprenger aerial parts."},"content":{"rendered":"<div class='ad_single_article'>\n<p class='ad_single_article_SO'><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-10-1\/#dianas-2021-10-1-e202103a04-dominguez-martin-etal-phytochemical-and-antitumoral-activity-studies-of-plectranthus-hadiensis-forssk-schweinf-ex-sprenger-aerial-parts'>dianas 10(1)<br \/><\/a> &gt; <a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2021-10-1-e202103a04-dominguez-martin-etal-phytochemical-and-antitumoral-activity-studies-of-plectranthus-hadiensis-forssk-schweinf-ex-sprenger-aerial-parts\/'>Dom\u00ednguez-Mart\u00edn etal<br \/><\/a><\/p>\n\n<p class='signature'>dianas | Vol 10 Num 1 | marzo  2021 | e202103a04<br \/><\/p>\n\n<p class='w_authors ad_single_article_authors'>Eva&nbsp;Mar\u00eda&nbsp;Dom\u00ednguez-Mart\u00edn<br&nbsp;\/>, Epole&nbsp;Ntungwe<br&nbsp;\/>, Catarina&nbsp;Teodosio<br&nbsp;\/>, Vera&nbsp;Isca<br&nbsp;\/>, Gabrielle&nbsp;Bangay<br&nbsp;\/>, Ana&nbsp;Mar\u00eda&nbsp;D\u00edaz-Lanza<br&nbsp;\/>, Patr\u00edcia&nbsp;Rijo<br&nbsp;\/><\/p>\n\n<p class='w_address ad_single_article_address'><b>1.&nbsp;<\/b>University of Alcal\u00e1 de Henares, Faculty of Pharmacy, Department of Biomedical Sciences, Pharmacology Area (Pharmacognosy Laboratory), New antitumor compounds: Toxic action on leukemia cells research group. Ctra. A2, Km 33.100 \u2013 Campus Universitario, 28805. Alcal\u00e1 de Henares, Madrid, Spain.<br \/>&nbsp; <b>2.&nbsp;<\/b>Universidade Lus\u00f3fona\u2019s Research Center for Biosciences &#038; Health Technologies-CBIOS,Bio.Natural Lab. Campo Grande 376, 1749-024 Lisbon, Portugal.<br \/>&nbsp; <b>3.&nbsp;<\/b>University of Lisbon, Faculty of Pharmacy, Instituto de Investiga\u00e7\u00e3o do Medicamento (iMed.ULisboa). 1649-003 Lisbon, Portugal.<br \/><\/p>\n\n<p class='w_mail ad_single_article_mail'><b><b>a<\/b><br \/>.&nbsp;<\/b>evam.dominguez@uah.es<br&nbsp;\/>&nbsp; <b><b>b<\/b><br \/>.&nbsp;<\/b>ana.diaz@uah.es<br&nbsp;\/>&nbsp; <b><b>c<\/b><br \/>.&nbsp;<\/b>patricia.rijo@ulusofona.pt<br&nbsp;\/><\/p>\n\n<p class='w_meeting ad_single_article_meeting'>VI Congreso de Se\u00f1alizaci\u00f3n Celular, SECUAH 2021.<br \/><br \/>\n29 de marzo a 30 de abril, 2021. Universidad de Alcal\u00e1. Alcal\u00e1 de Henares, Madrid. Espa\u00f1a.<br \/><\/p>\n\n<p class='w_abstract_caption ad_single_article_abstract_caption'>Resumen<\/p>\n<p class='w_abstract ad_single_article_abstract'>The Plectranthus genus belongs to the Lamiaceae family and consists of around 300 species distributed from Africa to Asia and Australia. Several studies have reported that Plectranthus species are rich in abietane-type diterpenes, such as royleanones, which are interesting in the treatment of various diseases. One of such species is Plectranthus hadiensis (Forssk.) Schweinf. ex Sprenger, which has been documented to be useful in several types of cancer (1). The objective of this work is to present the preliminary results of extraction, fractionation, isolation and bioactivity of the aerial parts of this plant. These data indicate a great difference between the acetonic extracts from leaves and those from stems, mainly in their content of 7a-acetoxy-6b-hydroxyroyleanone, which has cytotoxic properties (2,3). Currently, phytochemical studies are ongoing to elucidate the main abietanes responsible for the biological activity.<\/p><\/p>\n\n<div class='ad_single_article_citation_box'>\n<\/div>\n\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,65,56,64],"tags":[],"class_list":["post-493","post","type-post","status-publish","format-standard","hentry","category-article","category-dianas-vol-10-num-1","category-sesion-a","category-vols-10-19"],"_links":{"self":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts\/493","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/comments?post=493"}],"version-history":[{"count":0,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts\/493\/revisions"}],"wp:attachment":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/media?parent=493"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/categories?post=493"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/tags?post=493"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}