{"id":671,"date":"2017-03-15T10:05:27","date_gmt":"2017-03-15T10:05:27","guid":{"rendered":"http:\/\/www3.uah.es\/biologiadesistemas\/secuah2017\/?p=278"},"modified":"2017-03-15T10:05:27","modified_gmt":"2017-03-15T10:05:27","slug":"dianas-2017-6-1-e20170302a04-moreno-cubero-traf1-as-a-marker-of-exhaustion-during-chronic-hepatitis-c","status":"publish","type":"post","link":"https:\/\/dianas.web.uah.es\/journal\/dianas-2017-6-1-e20170302a04-moreno-cubero-traf1-as-a-marker-of-exhaustion-during-chronic-hepatitis-c\/","title":{"rendered":"Dianas 6 (1) Moreno-Cubero 2017 TRAF1 as a marker of exhaustion during chronic hepatitis C."},"content":{"rendered":"<div class='ad_single_article'>\n<p class='ad_single_article_SO'><a href='https:\/\/dianas.web.uah.es\/journal\/dianas-6-1\/#dianas-2017-6-1-e20170302a04-moreno-cubero-traf1-as-a-marker-of-exhaustion-during-chronic-hepatitis-c'>Dianas 6(1)<br \/><\/a> &gt; <a href='https:\/\/dianas.web.uah.es\/journal\/dianas-2017-6-1-e20170302a04-moreno-cubero-traf1-as-a-marker-of-exhaustion-during-chronic-hepatitis-c\/'>Moreno-Cubero<br \/><\/a><\/p>\n\n<p class='signature'>Dianas | Vol 6 Num 1 | marzo  2017 | e20170302a04<br \/><\/p>\n\n<p class='w_authors ad_single_article_authors'>Elia&nbsp;Moreno&nbsp;Cubero<br&nbsp;\/><\/p>\n\n<p class='w_address ad_single_article_address'>Hospital Universitario de Guadalajara.<br \/><\/p>\n\n<p class='w_mail ad_single_article_mail'>elia.morenocubero@gmail.com<br \/><\/p>\n\n<p class='w_meeting ad_single_article_meeting'>II Congreso de Se\u00f1alizaci\u00f3n Celular, SECUAH 2017.<br \/><br \/>\n14-16 de marzo, 2017. Universidad de Alcal\u00e1. Alcal\u00e1 de Henares, Madrid. Espa\u00f1a.<br \/><br \/>\nSesi\u00f3n 2a, Fisiolog\u00eda.<br \/><\/p>\n\n<p class='w_abstract_caption ad_single_article_abstract_caption'>Resumen<\/p>\n<p class='w_abstract ad_single_article_abstract'><strong>Antecedentes: <\/strong>Durante la infecci\u00f3n cr\u00f3nica por el virus de la hepatitis C (VHC), los linfocitos T citot\u00f3xicos (LTC)-VHC espec\u00edficos se encuentran agotados. Una de las razones por la cual esta respuesta se encuentra exhausta puede ser la disfuncionalidad de la v\u00eda co-estimuladora positiva miembro 9 de la superfamilia de receptores del factor de necrosis tumoral (FNT) (4-1BB) \/ y su ligando (4-1BBL) a trav\u00e9s de la p\u00e9rdida de uno de sus principales transductores de se\u00f1al, el factor asociado al receptor del FNT 1 (TRAF1).<\/p><\/p>\n\n<div class='ad_single_article_citation_box'>\n<\/div>\n\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,7,8,9,18,10,22,2],"tags":[],"class_list":["post-671","post","type-post","status-publish","format-standard","hentry","category-article","category-comunicacion","category-comunicacion-oral","category-dianas-vol-6-num-1","category-fisiologia","category-journal","category-sesion-2a","category-vols-1-9"],"_links":{"self":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts\/671","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/comments?post=671"}],"version-history":[{"count":0,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/posts\/671\/revisions"}],"wp:attachment":[{"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/media?parent=671"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/categories?post=671"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dianas.web.uah.es\/journal\/wp-json\/wp\/v2\/tags?post=671"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}